Q-omics provides the consensus-scored PRYP5 profile across patient tissues and cancer cell-line models. PRYP5 expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in KICH. Additionally, PRYP5 RNA expression shows 197 significant mutation-linked associations, with the highest sampling consensus in BRCA. Together, these results highlight KICH, and BRCA as cancer lineages where PRYP5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes PRYP5 survival associations across molecular data types. PRYP5 RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PRYP5 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	KICH (108)	view →

This table ranks reproducible PRYP5 RNA expression–survival associations across cancer types. High PRYP5 expression shows unfavorable associations in KICH, LUAD, CESC and ESCA. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for PRYP5 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.025	0.904	<.001	108	view →
LUAD	OS	Tertile	All	0.194	0.685	.004	72	view →
CESC	OS	Tertile	All	0.013	0.875	<.001	36	view →
ESCA	OS	Tertile	All	0.211	0.876	.028	18	view →

Pink = unfavorable, green = favorable. all 4 lineages →

PRYP5-KICH (DFS)

Kaplan–Meier survival curve for PRYP5 RNA expression in KICH: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with PRYP5 in patient tissues and cancer cell lines. In patient samples, PRYP5 shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Mutation	197	BRCA (159)	view →
RNA	111	BRCA (28)	view →