C15orf65

Across TCGA pan-cancer cohorts, C15orf65 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated C15orf65 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher C15orf65 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C15orf65 expression acts as an unfavorable survival marker, although some lineages such as UCEC and KIRP show a favorable association.

KICH, UCEC, and LGG are the cancer types where C15orf65 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.533	1.000	.003	74	view →
UCEC	OS	Median	All	0.792	0.511	<.001	72	view →
LGG	OS	Median	All	0.745	0.876	<.001	41	view →
LUSC	DFS	Tertile	II,III,IV	0.231	0.476	.001	36	view →
KIRP	DFS	Tertile	All	0.862	0.455	.002	35	view →
MESO	OS	Tertile	All	0.529	0.255	.003	32	view →
SARC	OS	Quartile	All	0.915	0.716	<.001	25	view →
LIHC	OS	Quartile	All	0.504	0.782	<.001	25	view →
THCA	DFS	Median	IV	0.968	0.750	.004	21	view →
ACC	DFS	Median	IV	0.572	0.170	.003	18	view →
BRCA	OS	Quartile	IV	0.798	0.234	.009	13	view →
CHOL	DFS	Tertile	All	0.858	0.248	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

C15orf65–KICH (OS)

Open the KICH breakdown →