C12orf76

Across TCGA patient cohorts, C12orf76 mutation is significantly associated with the RNA expression of many other genes, with 1,461 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf76-associated genes across cancer lineages are RN7SL488P, RBM17P3, and IGKV2-38. Each is linked with C12orf76 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf76-to-partner and partner-to-C12orf76 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL488P grouped by C12orf76-low versus C12orf76-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf76→partner) and Y-score (partner→C12orf76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL488P →	+0.215	+4.236	<.001	.008	3	2
COAD	RBM17P3 →	+0.044	+7.741	<.001	.009	3	1
COAD	IGKV2-38 →	+0.204	+7.741	<.001	.009	3	1
UCEC	EIF3M →	+0.528	+3.523	.003	.002	3	1
UCEC	PTPRJ →	+0.829	+2.609	<.001	.005	3	1
UCEC	LAMTOR1 →	+0.369	+2.818	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,461 associations by consensus.

RN7SL488P by C12orf76 expression — LUSC

Explore this box plot interactively →