acidic nuclear phosphoprotein 32 family member A pseudogene 1Genealiases: []
Q-omics provides the consensus-scored ANP32AP1 profile across patient tissues and cancer cell-line models. ANP32AP1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, ANP32AP1 is differentially expressed in 9, with the highest sampling consensus in COAD. Additionally, ANP32AP1 RNA expression shows 15,844 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and COAD as cancer lineages where ANP32AP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ANP32AP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ANP32AP1 survival associations across molecular data types. ANP32AP1 RNA expression shows survival associations in the most cancer types (25), followed by mutation status (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ANP32AP1 RNA expression–survival associations across cancer types. High ANP32AP1 expression shows unfavorable associations in ACC, LUSC, LGG and STAD, but favorable associations in CHOL and LUAD. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for ANP32AP1 RNA expression.
This table summarizes ANP32AP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for ANP32AP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ANP32AP1 shows higher tumor expression in COAD, HNSC, BRCA, LIHC, CHOL and LUSC. The COAD box plot shows higher ANP32AP1 RNA expression in tumor versus normal tissue (log2 FC = +0.329, t-test p = .001).
This table shows molecular features associated with ANP32AP1 in patient tissues and cancer cell lines. In patient samples, ANP32AP1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, ANP32AP1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_SCLC.
