ANP32AP1

Across TCGA patient cohorts, ANP32AP1 mutation is significantly associated with the RNA expression of many other genes, with 1,561 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANP32AP1-associated genes across cancer lineages are PPP1R26P4, RNU6-522P, and MTUS2-AS1. Each is linked with ANP32AP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANP32AP1-to-partner and partner-to-ANP32AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R26P4 grouped by ANP32AP1-low versus ANP32AP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32AP1→partner) and Y-score (partner→ANP32AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PPP1R26P4 →	+0.007	+3.356	<.001	.005	3	2
SKCM	RNU6-522P →	+0.165	+3.555	<.001	.003	3	2
UCEC	MTUS2-AS1 →	+0.233	+1.979	<.001	.002	3	2
UCEC	CDCA2 →	+0.653	+2.606	.003	.005	3	2
UCEC	NNT-AS1 →	+0.395	+2.637	.008	.005	3	2
UCEC	SHLD3 →	+0.449	+2.923	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,561 associations by consensus.

PPP1R26P4 by ANP32AP1 expression — SKCM

Explore this box plot interactively →