ALG1L13P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ALG1L13P mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG1L13P-associated genes across cancer lineages are RNU6-1331P, RNY3P11, and SNORD116-3. Each is linked with ALG1L13P in more than 1 cancer types. Because this analysis shows association rather than direction, both ALG1L13P-to-partner and partner-to-ALG1L13P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1331P grouped by ALG1L13P-low versus ALG1L13P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG1L13P→partner) and Y-score (partner→ALG1L13P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1331P →+0.640+5.081.001.00831
UCECRNY3P11 →+0.479+5.484.004.00531
UCECSNORD116-3 →+0.704+5.299<.001.00631
UCECSNORA10B →+0.551+5.031<.001.00931
UCECMIR218-1 →+0.598+4.982<.001.00931
UCECMTND4LP19 →+0.474+5.621<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

RNU6-1331P by ALG1L13P expression — UCEC

Box plot of RNU6-1331P in ALG1L13P-low vs ALG1L13P-high samples in UCEC.

Explore this box plot interactively →

Exploration