ALG1L13P

Across TCGA pan-cancer cohorts, ALG1L13P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ALG1L13P’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ALG1L13P RNA is repressed in tumor relative to normal tissue. In most cancer types ALG1L13P is over-expressed in tumor, although a few such as LUAD and LIHC show the opposite, repressed pattern.

LUAD, LIHC, and HNSC are the cancer types where ALG1L13P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ALG1L13P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	−0.526	<.001	9	view →
LIHC	All	III,IV	−0.874	<.001	8	view →
HNSC	Male	All	+0.660	<.001	8	view →
LUSC	All	II,III,IV	−0.630	<.001	6	view →
COAD	All	All	+0.314	<.001	6	view →
KICH	All	All	−0.216	<.001	4	view →
KIRP	All	IV	+0.452	.049	2	view →
KIRC	All	All	+0.149	.003	2	view →
READ	All	All	+0.622	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ALG1L13P–LUAD

Open the LUAD breakdown →