ALDH3B1

Across TCGA patient cohorts, ALDH3B1 mutation is significantly associated with the RNA expression of many other genes, with 4,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALDH3B1-associated genes across cancer lineages are VN1R91P, RNU7-56P, and MIR5583-1. Each is linked with ALDH3B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDH3B1-to-partner and partner-to-ALDH3B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R91P grouped by ALDH3B1-low versus ALDH3B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH3B1→partner) and Y-score (partner→ALDH3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VN1R91P →	+0.154	+2.551	<.001	.002	3	2
BRCA	RNU7-56P →	+0.839	+5.148	<.001	.008	3	2
BRCA	MIR5583-1 →	+0.649	+6.112	<.001	.002	3	2
UCEC	RNU6-391P →	+0.147	+2.568	<.001	.005	3	2
COAD	RNA5SP207 →	+1.534	+4.870	<.001	.002	3	2
COAD	MIR3137 →	+0.649	+5.392	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,023 associations by consensus.

VN1R91P by ALDH3B1 expression — UCEC

Explore this box plot interactively →