RNA, U6 small nuclear 391, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-391P profile across patient tissues and cancer cell-line models. RNU6-391P expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, RNU6-391P is differentially expressed in 1, with the highest sampling consensus in STAD. Additionally, RNU6-391P RNA expression shows 5,857 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UCS, and STAD as cancer lineages where RNU6-391P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-391P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-391P survival associations across molecular data types. RNU6-391P RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-391P RNA expression–survival associations across cancer types. High RNU6-391P expression shows unfavorable associations in UCS, HNSC, SARC, CHOL, TGCT and ESCA. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .009). Together, the overview and detailed table identify UCS as the clearest survival context for RNU6-391P RNA expression.
This table summarizes RNU6-391P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-391P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-391P shows higher tumor expression in STAD. The STAD box plot shows higher RNU6-391P RNA expression in tumor versus normal tissue (log2 FC = +0.060, t-test p = .039).
This table shows molecular features associated with RNU6-391P in patient tissues and cancer cell lines. In patient samples, RNU6-391P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
