RNU6-391P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-391P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-391P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-391P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-391P expression acts as an unfavorable survival marker.

UCS, HNSC, and SARC are the cancer types where RNU6-391P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSOSTertileAll0.1350.687.00972view →
HNSCDFSTertileII,III,IV0.1630.685.01154view →
SARCOSTertileAll0.0220.861<.00136view →
CHOLOSTertileII,III,IV0.0240.601.02527view →
TGCTOSTertileAll0.7950.983.00818view →
PAADDFSTertileII,III,IV0.2130.440.0279view →
ESCAOSTertileAll0.4700.906.0179view →
STADDFSTertileIV0.0830.379.0019view →
LUADOSTertileAll0.2500.812.0359view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration