AHSG

Across TCGA patient cohorts, AHSG mutation is significantly associated with the RNA expression of many other genes, with 1,260 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AHSG-associated genes across cancer lineages are RNU6-42P, DUSP14, and BLOC1S2P1. Each is linked with AHSG in more than 2 cancer types. Because this analysis shows association rather than direction, both AHSG-to-partner and partner-to-AHSG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-42P grouped by AHSG-low versus AHSG-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHSG→partner) and Y-score (partner→AHSG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-42P →	+1.439	+3.842	<.001	.005	3	3
SKCM	DUSP14 →	+0.838	+3.465	<.001	.003	3	2
SKCM	BLOC1S2P1 →	+0.079	+2.817	<.001	.005	3	2
HNSC	PRYP2 →	+0.074	+7.954	<.001	.008	3	2
LUAD	RNA5SP139 →	+0.410	+2.231	.001	.005	3	2
LUAD	TSEN2P1 →	+0.179	+3.061	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,260 associations by consensus.

RNU6-42P by AHSG expression — COAD

Explore this box plot interactively →