ABI3BP

Across TCGA cell cohorts, ABI3BP mutation is significantly associated with the mutation status of many other genes, with 5,979 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABI3BP-associated genes across cancer lineages are ITGAM, RREB1, and NDNF. Each is linked with ABI3BP in more than 4 cancer types. Because this analysis shows association rather than direction, both ABI3BP-to-partner and partner-to-ABI3BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGAM grouped by ABI3BP-low versus ABI3BP-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI3BP→partner) and Y-score (partner→ABI3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ITGAM →	+5.014	+5.584	.003	.003	1	5
UPPER_AERODIGESTIVE_TRACT	RREB1 →	+4.954	+4.392	.008	.008	1	5
PANCREAS	NDNF →	+5.115	+5.115	.005	.005	1	4
OVARY	MEGF10 →	+4.217	+4.217	.001	.001	1	4
BLOOD_Leukemia	ACACA →	+4.309	+4.560	.007	.007	1	4
LARGE_INTESTINE	ZMIZ1 →	+1.892	+2.548	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,979 associations by consensus.

ITGAM by ABI3BP expression — BLOOD_Lymphoma

Explore this box plot interactively →