ABI3BP

Across TCGA pan-cancer cohorts, ABI3BP RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of ABI3BP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ABI3BP RNA is repressed in tumor relative to normal tissue. In most cancer types ABI3BP is over-expressed in tumor, although a few such as COAD and BLCA show the opposite, repressed pattern.

COAD, BLCA, and KICH are the cancer types where ABI3BP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABI3BP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−2.543	<.001	12	view →
BLCA	Male	IV	−4.340	<.001	11	view →
KICH	Female	All	−3.095	<.001	10	view →
THCA	Male	All	−2.370	<.001	10	view →
LUSC	Female	All	−3.331	<.001	9	view →
LUAD	Female	III,IV	−2.999	<.001	9	view →
UCEC	All	III,IV	−4.183	<.001	8	view →
HNSC	Male	All	−1.372	<.001	8	view →
BRCA	All	III,IV	−2.131	<.001	6	view →
KIRC	Male	All	+0.894	<.001	6	view →
STAD	All	All	−1.832	<.001	5	view →
LIHC	Male	III,IV	−0.588	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

ABI3BP–COAD

Open the COAD breakdown →