ABI3BP

Across TCGA pan-cancer cohorts, ABI3BP RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ABI3BP data layer compared with 6 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ABI3BP RNA is associated with better overall survival. In most high-consensus cancer types, elevated ABI3BP expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, KICH, and KIRP are the cancer types where ABI3BP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.741	0.521	<.001	103	view →
KICH	OS	Median	All	0.748	1.000	.001	87	view →
KIRP	DFS	Tertile	All	0.963	0.829	<.001	77	view →
ACC	OS	Tertile	All	0.905	0.444	<.001	74	view →
LUAD	OS	Tertile	All	0.769	0.631	.002	58	view →
LGG	DFS	Median	All	0.797	0.676	<.001	35	view →
SKCM	OS	Quartile	II,III,IV	0.940	0.670	<.001	28	view →
HNSC	DFS	Quartile	IV	0.770	0.560	.006	20	view →
BLCA	OS	Tertile	All	0.327	0.540	.012	18	view →
ESCA	OS	Median	IV	0.222	0.698	.006	18	view →
DLBC	OS	Tertile	II,III,IV	1.000	0.267	.008	17	view →
MESO	OS	Quartile	All	0.294	0.514	.014	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ABI3BP–KIRC (OS)

Open the KIRC breakdown →