A2M-AS1

Across TCGA patient cohorts, A2M-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,877 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible A2M-AS1-associated proteins across cancer lineages are DDAH2, NFATC2, and DPYSL2. Each is linked with A2M-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both A2M-AS1-to-partner and partner-to-A2M-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, A2M-AS1 versus DDAH2 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (A2M-AS1→partner) and Y-score (partner→A2M-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DDAH2 →	+0.477	+0.802	<.001	<.001	3	8
COAD	NFATC2 →	+0.654	+0.259	.001	.002	3	7
HNSC	DPYSL2 →	+0.424	+0.823	<.001	<.001	3	7
HNSC	TBC1D2B →	+0.280	+0.845	<.001	<.001	3	7
UCEC	TMOD2 →	+0.510	+0.549	<.001	<.001	3	7
HNSC	SYNPO2 →	+0.928	+0.723	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,877 associations by consensus.

A2M-AS1 vs DDAH2 — HNSC

Explore this scatter interactively →