"Phagocytosis, recognition"

Across TCGA patient cohorts, RNA activity of the "Phagocytosis, recognition" pathway is significantly associated with the RNA expression of multiple genes, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are SNAI1, ADGRF5, and MMP19, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, "Phagocytosis, recognition" activity versus SNAI1 in OV (Pearson r = 0.27).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SNAI1 →	+0.928	+0.224	.003	<.001	3	6
OV	ADGRF5 →	+0.729	+0.165	<.001	<.001	3	6
HNSC	MMP19 →	+0.678	+0.211	.001	.001	3	5
COAD	TNFAIP6 →	+1.244	+0.261	.003	.003	3	5
OV	ADAM8 →	+0.976	+0.245	<.001	<.001	3	5
COAD	LILRB3 →	+0.783	+0.240	.003	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0006910 vs SNAI1 — OV

Explore this scatter interactively →