ZNF701

Across TCGA patient cohorts, ZNF701 protein abundance is significantly associated with the RNA expression of many other genes, with 92 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF701-associated genes across cancer lineages are C22orf31, FZD10, and HMGXB3. Each is linked with ZNF701 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF701-to-partner and partner-to-ZNF701 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF701 versus C22orf31 in GBM, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF701→partner) and Y-score (partner→ZNF701) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	C22orf31 →	-0.714	-0.711	.001	<.001	3	1
GBM	FZD10 →	+0.360	+0.435	<.001	.002	3	1
GBM	HMGXB3 →	+0.416	+0.732	.005	<.001	3	1
GBM	MRPS15 →	+0.227	+0.417	.008	.003	3	1
GBM	MRPS14 →	-0.454	-0.435	.002	.002	3	1
GBM	IGLL1 →	+0.204	+0.622	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

ZNF701 vs C22orf31 — GBM

Explore this scatter interactively →