ZNF701

Across TCGA pan-cancer cohorts, ZNF701 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ZNF701 data layer compared with 6 for mutation status.

The strongest signal is observed in brain lower grade glioma (LGG), where higher ZNF701 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF701 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

LGG, KIRC, and HNSC are the cancer types where ZNF701 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.640	0.841	<.001	54	view →
KIRC	DFS	Quartile	All	0.755	0.477	.001	44	view →
HNSC	DFS	Median	IV	0.712	0.570	.001	41	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
UVM	DFS	Quartile	III,IV	0.170	0.814	.001	21	view →
MESO	DFS	Quartile	III,IV	0.248	0.481	.010	15	view →
ACC	DFS	Tertile	All	0.447	0.751	.008	14	view →
LUAD	DFS	Median	IV	0.711	0.300	.017	13	view →
READ	DFS	Median	IV	0.353	0.794	.003	13	view →
BRCA	OS	Quartile	IV	0.716	0.221	.005	9	view →
LUSC	DFS	Quartile	All	0.330	0.507	.017	7	view →
KICH	DFS	Median	III,IV	0.410	0.843	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ZNF701–LGG (DFS)

Open the LGG breakdown →