ZNF343

Across TCGA patient cohorts, ZNF343 mutation is significantly associated with the RNA expression of many other genes, with 1,282 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF343-associated genes across cancer lineages are RNU6-1313P, ANHX, and GLRX5P1. Each is linked with ZNF343 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF343-to-partner and partner-to-ZNF343 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1313P grouped by ZNF343-low versus ZNF343-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF343→partner) and Y-score (partner→ZNF343) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-1313P →	+0.260	+4.191	<.001	.009	3	3
LUSC	ANHX →	+0.426	+4.738	<.001	<.001	3	3
UCEC	GLRX5P1 →	+0.467	+2.083	<.001	.005	3	3
UCEC	RNA5SP519 →	+0.521	+2.661	<.001	<.001	3	3
BLCA	NIFKP3 →	+0.145	+3.436	<.001	.001	3	2
BLCA	SNORA59B →	+0.108	+2.948	.009	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,282 associations by consensus.

RNU6-1313P by ZNF343 expression — LUSC

Explore this box plot interactively →