Q-omics provides the consensus-scored ANHX profile across patient tissues and cancer cell-line models. ANHX expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in CHOL. Among the 18 cancer types available for tumor–normal comparison, ANHX is differentially expressed in 3, with the highest sampling consensus in KIRC. Additionally, ANHX RNA expression shows 7,359 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight CHOL, KIRC, and TGCT as cancer lineages where ANHX shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ANHX — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ANHX survival associations across molecular data types. ANHX RNA expression shows survival associations in the most cancer types (15), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ANHX RNA expression–survival associations across cancer types. High ANHX expression shows unfavorable associations in CHOL, PAAD, ACC, SKCM and PCPG, but favorable associations in UCS. The CHOL Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CHOL as the clearest survival context for ANHX RNA expression.
This table summarizes ANHX tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for ANHX. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ANHX shows higher tumor expression in KIRC, KICH and HNSC. The KIRC box plot shows higher ANHX RNA expression in tumor versus normal tissue (log2 FC = +0.008, t-test p = .025).
This table shows molecular features associated with ANHX in patient tissues and cancer cell lines. In patient samples, ANHX shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, ANHX RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LIVER, while CRISPR and shRNA rows add functional-dependency signals in URINARY_TRACT and LARGE_INTESTINE.
