Across TCGA cell cohorts, ANHX mutation is significantly associated with the mutation status of many other genes, with 1,637 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANHX-associated genes across cancer lineages are BICRA, ELFN1, and PDS5B. Each is linked with ANHX in more than 3 cancer types. Because this analysis shows association rather than direction, both ANHX-to-partner and partner-to-ANHX results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANHX→partner) and Y-score (partner→ANHX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BICRA →	+2.070	+2.807	.002	.002	1	4
STOMACH	ELFN1 →	+4.807	+4.807	.008	.008	1	4
STOMACH	PDS5B →	+4.807	+4.807	.008	.008	1	4
SKIN	GSE1 →	+3.053	+3.718	.006	.006	1	4
LUNG_NSCLC_LUAD	VIRMA →	+3.602	+4.851	.002	.002	1	3
LUNG_NSCLC_LUAD	COL6A5 →	+2.924	+4.334	.006	.006	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,637 associations by consensus.

Exploration

ANHX survival (RNA) · tumor vs normal (RNA) · all ANHX data types