Across TCGA patient cohorts, ANHX mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANHX-associated genes across cancer lineages are SF2, VEGFR2, and YAP. Each is linked with ANHX in more than 1 cancer types. Because this analysis shows association rather than direction, both ANHX-to-partner and partner-to-ANHX results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANHX→partner) and Y-score (partner→ANHX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SF2 →	-0.213	-3.308	<.001	.010	3	1
UCEC	VEGFR2 →	+0.381	+2.183	.014	.035	3	1
UCEC	YAP →	+0.175	+3.321	.026	.010	3	1
UCEC	TIGAR →	+0.243	+3.348	.002	.005	2	1
UCEC	TFRC →	+0.584	+3.321	.035	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ANHX survival (RNA) · tumor vs normal (RNA) · all ANHX data types