ZNF343

Across TCGA pan-cancer cohorts, ZNF343 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ZNF343 data layer compared with 3 for mutation status.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ZNF343 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF343 expression acts as an unfavorable survival marker, although some lineages such as THYM and READ show a favorable association.

LIHC, MESO, and COAD are the cancer types where ZNF343 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.463	0.619	<.001	88	view →
MESO	DFS	Quartile	All	0.225	0.518	<.001	87	view →
COAD	DFS	Quartile	III,IV	0.293	0.743	<.001	76	view →
KICH	DFS	Median	III,IV	0.240	1.000	.001	38	view →
THYM	DFS	Tertile	II,III,IV	1.000	0.551	.006	37	view →
KIRC	DFS	Median	II,III,IV	0.438	0.643	.001	34	view →
READ	OS	Median	II,III,IV	0.805	0.420	.002	34	view →
LGG	DFS	Quartile	All	0.633	0.837	<.001	33	view →
KIRP	DFS	Median	All	0.347	0.712	<.001	25	view →
UCEC	DFS	Median	All	0.795	0.878	.002	24	view →
STAD	OS	Median	II,III,IV	0.475	0.656	.021	18	view →
LUSC	DFS	Quartile	III,IV	0.486	1.000	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ZNF343–LIHC (DFS)

Open the LIHC breakdown →