ZNF343

Across TCGA cell cohorts, ZNF343 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ZNF343-associated genes across cancer lineages are KCNG4, USP17L4, and RLN3. Each is linked with ZNF343 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF343-to-partner and partner-to-ZNF343 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNG4 grouped by ZNF343-low versus ZNF343-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF343→partner) and Y-score (partner→ZNF343) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KCNG4 →	+0.013	+4.807	<.001	.006	3	2
BLOOD_Myeloma	USP17L4 →	+0.040	+4.807	<.001	.006	3	1
BREAST	RLN3 →	+0.088	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR1L1 →	+0.018	+4.887	<.001	.009	3	1
BLOOD_Leukemia	TEX51 →	+0.574	+5.969	<.001	.001	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

KCNG4 by ZNF343 expression — BLOOD_Myeloma

Explore this box plot interactively →