Q-omics provides the consensus-scored TEX51 profile across patient tissues and cancer cell-line models. TEX51 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, TEX51 is differentially expressed in 2, with the highest sampling consensus in KIRP. Additionally, TEX51 RNA expression shows 6,352 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRP, and STAD as cancer lineages where TEX51 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TEX51 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TEX51 survival associations across molecular data types. TEX51 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TEX51 RNA expression–survival associations across cancer types. High TEX51 expression shows unfavorable associations in KIRP, SKCM, BLCA, LIHC, DLBC and SARC. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for TEX51 RNA expression.
This table summarizes TEX51 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for TEX51. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TEX51 shows lower tumor expression in KIRP and KICH. The KIRP box plot shows higher TEX51 RNA expression in normal versus tumor tissue (log2 FC = −0.600, t-test p < 0.001).
This table shows molecular features associated with TEX51 in patient tissues and cancer cell lines. In patient samples, TEX51 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, TEX51 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Lymphoma.
