ZNF114

Across TCGA patient cohorts, ZNF114 mutation is significantly associated with the RNA expression of many other genes, with 1,958 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF114-associated genes across cancer lineages are SYPL1P1, RNA5SP55, and MIR2115. Each is linked with ZNF114 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF114-to-partner and partner-to-ZNF114 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYPL1P1 grouped by ZNF114-low versus ZNF114-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF114→partner) and Y-score (partner→ZNF114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SYPL1P1 →	+0.121	+4.693	<.001	.007	3	2
COAD	RNA5SP55 →	+0.747	+4.790	<.001	.006	3	2
BRCA	MIR2115 →	+0.687	+5.203	<.001	.007	3	2
SKCM	MIR6783 →	+0.396	+2.287	.001	.007	3	2
BRCA	MDH1P2 →	+0.060	+5.175	.001	.007	3	2
UCEC	RAD54L2 →	+0.342	+2.502	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,958 associations by consensus.

SYPL1P1 by ZNF114 expression — COAD

Explore this box plot interactively →