ZBTB7A

Across TCGA patient cohorts, ZBTB7A mutation is significantly associated with the RNA expression of many other genes, with 2,018 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB7A-associated genes across cancer lineages are MIR3193, RNA5SP67, and SDR42E1P2. Each is linked with ZBTB7A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB7A-to-partner and partner-to-ZBTB7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3193 grouped by ZBTB7A-low versus ZBTB7A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB7A→partner) and Y-score (partner→ZBTB7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3193 →	+0.494	+1.838	<.001	.004	3	2
LUSC	RNA5SP67 →	+0.329	+4.261	.005	.008	3	2
LUSC	SDR42E1P2 →	+0.133	+4.792	<.001	.006	3	2
SKCM	SNORD38A →	+0.431	+3.451	.003	.006	3	2
PRAD	LACRT →	+0.068	+5.563	<.001	.004	3	1
PRAD	TRAJ33 →	+0.685	+5.166	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,018 associations by consensus.

MIR3193 by ZBTB7A expression — UCEC

Explore this box plot interactively →