small nucleolar RNA, C/D box 38AGenealiases: RNU38A · U38A
Q-omics provides the consensus-scored SNORD38A profile across patient tissues and cancer cell-line models. SNORD38A expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, SNORD38A is differentially expressed in 4, with the highest sampling consensus in COAD. Additionally, SNORD38A RNA expression shows 6,130 significant pathway-activity associations, with the highest sampling consensus in UCEC. Together, these results highlight UVM, COAD, and UCEC as cancer lineages where SNORD38A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD38A — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD38A survival associations across molecular data types. SNORD38A RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD38A RNA expression–survival associations across cancer types. High SNORD38A expression shows unfavorable associations in UVM, BRCA, KIRC, BLCA, PCPG and THYM. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .008). Together, the overview and detailed table identify UVM as the clearest survival context for SNORD38A RNA expression.
This table summarizes SNORD38A tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD38A. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD38A shows higher tumor expression in COAD, UCEC, LUAD and LIHC. The COAD box plot shows higher SNORD38A RNA expression in tumor versus normal tissue (log2 FC = +1.751, t-test p < 0.001).
This table shows molecular features associated with SNORD38A in patient tissues and cancer cell lines. In patient samples, SNORD38A shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.
