tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 5Genealiases: []
Q-omics provides the consensus-scored YWHAEP5 profile across patient tissues and cancer cell-line models. YWHAEP5 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, YWHAEP5 is differentially expressed in 8, with the highest sampling consensus in BLCA. Additionally, YWHAEP5 RNA expression shows 17,544 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight KIRC, BLCA, and ACC as cancer lineages where YWHAEP5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for YWHAEP5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes YWHAEP5 survival associations across molecular data types. YWHAEP5 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible YWHAEP5 RNA expression–survival associations across cancer types. High YWHAEP5 expression shows unfavorable associations in BLCA and LUAD, but favorable associations in KIRC, BRCA, UCS and READ. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for YWHAEP5 RNA expression.
This table summarizes YWHAEP5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for YWHAEP5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. YWHAEP5 shows lower tumor expression in KICH and THCA and higher tumor expression in BLCA, HNSC, COAD and LUSC. The BLCA box plot shows higher YWHAEP5 RNA expression in tumor versus normal tissue (log2 FC = +0.338, t-test p < 0.001).
This table shows molecular features associated with YWHAEP5 in patient tissues and cancer cell lines. In patient samples, YWHAEP5 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
