YIPF1

Across TCGA patient cohorts, YIPF1 mutation is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF1-associated genes across cancer lineages are RN7SL505P, MIR4499, and MMP12. Each is linked with YIPF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF1-to-partner and partner-to-YIPF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL505P grouped by YIPF1-low versus YIPF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF1→partner) and Y-score (partner→YIPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL505P →	+0.247	+3.061	.004	<.001	3	2
SKCM	MIR4499 →	+0.443	+3.656	.002	.003	3	2
UCEC	MMP12 →	+1.411	+3.480	.006	.002	3	1
UCEC	CCDC58P1 →	+0.396	+2.478	<.001	.003	3	1
UCEC	MIR3153 →	+1.000	+2.741	.001	.009	3	1
UCEC	MIR3690 →	+0.457	+2.738	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

RN7SL505P by YIPF1 expression — UCEC

Explore this box plot interactively →