Q-omics provides the consensus-scored MIR4499 profile across patient tissues and cancer cell-line models. MIR4499 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, MIR4499 is differentially expressed in 2, with the highest sampling consensus in KIRC. Additionally, MIR4499 RNA expression shows 5,790 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight READ, KIRC, and STAD as cancer lineages where MIR4499 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4499 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4499 survival associations across molecular data types. MIR4499 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4499 RNA expression–survival associations across cancer types. High MIR4499 expression shows unfavorable associations in READ, COAD, CHOL, STAD and THCA, but favorable associations in PAAD. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for MIR4499 RNA expression.
This table summarizes MIR4499 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4499. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4499 shows higher tumor expression in KIRC and STAD. The KIRC box plot shows higher MIR4499 RNA expression in tumor versus normal tissue (log2 FC = +0.181, t-test p = .016).
This table shows molecular features associated with MIR4499 in patient tissues and cancer cell lines. In patient samples, MIR4499 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
