MIR4499

Across TCGA patient cohorts, MIR4499 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,790 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4499-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Positive regulation of proteolysis involved in protein catabolic process, and Monosaccharide metabolic process. Each is linked with MIR4499 in more than 8 cancer types. Because this analysis shows association rather than direction, both MIR4499-to-partner and partner-to-MIR4499 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by MIR4499-low versus MIR4499-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4499→partner) and Y-score (partner→MIR4499) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Establishment of protein localization to membrane →	+0.049	+0.268	<.001	<.001	3	9
STAD	Positive regulation of proteolysis involved in protein catabolic process →	+0.048	+0.261	<.001	<.001	3	9
STAD	Monosaccharide metabolic process →	+0.045	+0.226	<.001	<.001	3	9
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.051	+0.259	<.001	<.001	3	8
STAD	Pyruvate metabolic process →	+0.045	+0.216	<.001	<.001	3	8
STAD	Translational elongation →	+0.046	+0.235	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,790 associations by consensus.

Establishment of protein localization to membrane by MIR4499 expression — STAD

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