MIR4499

Across TCGA pan-cancer cohorts, MIR4499 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR4499 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher MIR4499 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4499 expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

READ, COAD, and PAAD are the cancer types where MIR4499 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	II,III,IV	0.532	0.835	<.001	90	view →
COAD	OS	Tertile	All	0.281	0.695	.004	72	view →
PAAD	OS	Tertile	II,III,IV	0.977	0.382	.005	54	view →
CHOL	OS	Tertile	II,III,IV	0.019	0.765	.001	45	view →
STAD	DFS	Tertile	IV	0.097	0.412	.008	18	view →
THCA	DFS	Tertile	IV	0.027	0.937	<.001	18	view →
GBM	DFS	Tertile	All	0.074	0.296	<.001	9	view →
BLCA	OS	Tertile	IV	0.410	0.602	.045	9	view →
SKCM	OS	Tertile	III,IV	0.157	0.468	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MIR4499–READ (DFS)

Open the READ breakdown →