Across TCGA patient cohorts, XRCC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,575 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible XRCC2-associated proteins across cancer lineages are RIF1, RRM2, and SETDB1_S1066. Each is linked with XRCC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both XRCC2-to-partner and partner-to-XRCC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (XRCC2→partner) and Y-score (partner→XRCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIF1 →	+0.490	+1.070	<.001	<.001	3	10
UCEC	RRM2 →	+0.856	+1.194	<.001	<.001	3	10
GBM	SETDB1_S1066 →	+0.958	+1.210	<.001	<.001	3	10
UCEC	SMC2 →	+0.763	+1.186	<.001	<.001	3	10
GBM	SMC4 →	+0.713	+1.151	<.001	<.001	3	10
LUAD	TOP2A_S1106 →	+1.236	+1.184	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,575 associations by consensus.

Exploration

XRCC2 survival (RNA) · tumor vs normal (RNA) · all XRCC2 data types