WDR74

Across TCGA patient cohorts, WDR74 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR74-associated proteins across cancer lineages are SSRP1, SUPT16H, and POLR1E. Each is linked with WDR74 in more than 7 cancer types. Because this analysis shows association rather than direction, both WDR74-to-partner and partner-to-WDR74 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR74 versus SSRP1 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR74→partner) and Y-score (partner→WDR74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SSRP1 →	+0.429	+0.376	<.001	.003	3	8
OV	SUPT16H →	+0.509	+0.437	<.001	<.001	3	8
BRCA	POLR1E →	+0.431	+0.584	<.001	<.001	3	8
LSCC	CMSS1 →	+0.461	+0.420	<.001	<.001	3	8
GBM	CPSF7 →	+0.374	+0.338	<.001	<.001	3	8
LSCC	MRTO4 →	+0.374	+0.557	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,886 associations by consensus.

WDR74 vs SSRP1 — OV

Explore this scatter interactively →