WDR70

Across TCGA patient cohorts, WDR70 mutation is significantly associated with the RNA expression of many other genes, with 2,915 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR70-associated genes across cancer lineages are OR4D9, HMG20B, and OR51A8P. Each is linked with WDR70 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR70-to-partner and partner-to-WDR70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D9 grouped by WDR70-low versus WDR70-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR70→partner) and Y-score (partner→WDR70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR4D9 →	+0.101	+3.024	<.001	<.001	3	3
HNSC	HMG20B →	+0.519	+3.356	.004	.005	3	2
LUAD	OR51A8P →	+0.283	+5.629	<.001	<.001	3	2
LUAD	SOCS2P2 →	+0.346	+5.037	<.001	.002	3	2
LUAD	LINC01809 →	+0.168	+6.333	<.001	<.001	3	2
LUAD	MIR6752 →	+0.639	+4.888	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,915 associations by consensus.

OR4D9 by WDR70 expression — HNSC

Explore this box plot interactively →