WDR70

Across TCGA pan-cancer cohorts, WDR70 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of WDR70’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where WDR70 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WDR70 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, KIRC, and LIHC are the cancer types where WDR70 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR70 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.601	<.001	11	view →
KIRC	Female	All	+0.387	<.001	11	view →
LIHC	Male	II,III,IV	+0.965	<.001	9	view →
LUAD	Male	III,IV	+0.550	<.001	9	view →
LUSC	Female	All	+0.817	<.001	7	view →
STAD	All	All	+0.508	<.001	6	view →
THCA	All	All	−0.200	<.001	6	view →
CHOL	Male	All	+1.768	<.001	5	view →
COAD	Male	All	+0.339	<.001	5	view →
BLCA	All	All	+0.336	.014	5	view →
KICH	Female	All	−0.867	.001	3	view →
KIRP	All	IV	+0.652	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

WDR70–HNSC

Open the HNSC breakdown →