VEZT

Across TCGA patient cohorts, VEZT mutation is significantly associated with the RNA expression of many other genes, with 1,328 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VEZT-associated genes across cancer lineages are TAS2R16, RN7SL248P, and KIR2DP1. Each is linked with VEZT in more than 2 cancer types. Because this analysis shows association rather than direction, both VEZT-to-partner and partner-to-VEZT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R16 grouped by VEZT-low versus VEZT-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEZT→partner) and Y-score (partner→VEZT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TAS2R16 →	+0.063	+4.505	<.001	.009	3	3
BRCA	RN7SL248P →	+0.133	+5.786	<.001	.001	3	2
READ	KIR2DP1 →	+0.108	+5.925	<.001	.002	3	2
UCEC	TAF9 →	+0.433	+2.169	.001	.003	3	2
UCEC	MIR8082 →	+0.300	+1.909	<.001	.004	3	2
LUAD	RNU6-421P →	+0.488	+4.984	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,328 associations by consensus.

TAS2R16 by VEZT expression — HNSC

Explore this box plot interactively →