VEZT

Across TCGA pan-cancer cohorts, VEZT RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated VEZT data layer compared with 6 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher VEZT RNA is associated with better overall survival. In most high-consensus cancer types, elevated VEZT expression acts as an unfavorable survival marker, although some lineages such as UCS and LUAD show a favorable association.

UCS, KIRP, and HNSC are the cancer types where VEZT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Quartile	II,III,IV	0.771	0.183	.001	80	view →
KIRP	DFS	Quartile	All	0.763	0.941	.001	78	view →
HNSC	OS	Median	III,IV	0.559	0.778	.003	69	view →
CESC	DFS	Median	All	0.673	0.803	.007	52	view →
LIHC	DFS	Median	All	0.468	0.613	<.001	51	view →
MESO	OS	Median	III,IV	0.449	0.659	.004	31	view →
PAAD	OS	Median	All	0.284	0.524	.003	26	view →
UVM	DFS	Quartile	III,IV	0.193	0.814	.003	25	view →
LUAD	DFS	Median	IV	0.656	0.297	.021	20	view →
LUSC	DFS	Tertile	III,IV	0.415	1.000	.013	19	view →
BRCA	DFS	Quartile	III,IV	0.915	0.787	.009	18	view →
LGG	OS	Median	All	0.754	0.910	<.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

VEZT–UCS (OS)

Open the UCS breakdown →