Q-omics provides the consensus-scored RNU6-421P profile across patient tissues and cancer cell-line models. RNU6-421P expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, RNU6-421P RNA expression shows 7,535 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight BLCA, and COAD as cancer lineages where RNU6-421P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-421P survival associations across molecular data types. RNU6-421P RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-421P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	16	BLCA (126)	view →

This table ranks reproducible RNU6-421P RNA expression–survival associations across cancer types. High RNU6-421P expression shows unfavorable associations in BLCA, ACC, LUAD, COAD, LUSC and THCA. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for RNU6-421P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	IV	0.107	0.593	<.001	126	view →
ACC	OS	Tertile	All	0.168	0.821	<.001	72	view →
LUAD	OS	Tertile	II,III,IV	0.111	0.750	<.001	60	view →
COAD	DFS	Tertile	III,IV	0.161	0.654	.001	45	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
THCA	OS	Tertile	III,IV	0.171	0.788	<.001	36	view →

Pink = unfavorable, green = favorable. all 16 lineages →

RNU6-421P-BLCA (OS)

Kaplan–Meier survival curve for RNU6-421P RNA expression in BLCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-421P in patient tissues and cancer cell lines. In patient samples, RNU6-421P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,535	COAD (2283)	view →
Function (RNA)	6,095	STAD (5393)	view →