VEGFD

Across TCGA cell cohorts, VEGFD mutation is significantly associated with the mutation status of many other genes, with 482 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VEGFD-associated genes across cancer lineages are ELMOD1, ZNF132, and TLR4. Each is linked with VEGFD in more than 1 cancer types. Because this analysis shows association rather than direction, both VEGFD-to-partner and partner-to-VEGFD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELMOD1 grouped by VEGFD-low versus VEGFD-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFD→partner) and Y-score (partner→VEGFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ELMOD1 →	+4.339	+4.339	.009	.009	1	2
LUNG_NSCLC_LUAD	ZNF132 →	+4.339	+4.339	.009	.009	1	2
LUNG_NSCLC_LUAD	TLR4 →	+2.754	+4.189	.008	.008	1	2
LUNG_NSCLC_LUAD	CIR1 →	+3.924	+5.063	.001	.001	1	2
LUNG_NSCLC_LUAD	FARP1 →	+5.339	+4.772	.004	.004	1	2
LUNG_NSCLC_LUAD	NMNAT2 →	+5.339	+4.772	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 482 associations by consensus.

ELMOD1 by VEGFD expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →