VEGFC

Across TCGA patient cohorts, VEGFC protein abundance is significantly associated with the RNA expression of many other genes, with 6,188 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VEGFC-associated genes across cancer lineages are CCN4, PCOLCE, and AEBP1. Each is linked with VEGFC in more than 3 cancer types. Because this analysis shows association rather than direction, both VEGFC-to-partner and partner-to-VEGFC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VEGFC versus CCN4 in LUAD, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VEGFC→partner) and Y-score (partner→VEGFC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCN4 →	+1.148	+0.761	<.001	<.001	3	4
BRCA	PCOLCE →	+1.005	+0.696	.003	.001	3	4
BRCA	AEBP1 →	+1.830	+0.951	<.001	<.001	3	4
BRCA	COL1A1 →	+2.165	+1.097	<.001	<.001	3	4
PDAC	PPFIBP1 →	+0.692	+0.726	<.001	<.001	3	4
BRCA	COL12A1 →	+1.558	+0.899	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,188 associations by consensus.

VEGFC vs CCN4 — LUAD

Explore this scatter interactively →