UVRAG-DT

Across TCGA patient cohorts, UVRAG-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,104 significant associations in total. STAD shows the largest number of these associations.

The most reproducible UVRAG-DT-associated GO terms across cancer lineages are Negative regulation of centrosome duplication, Transport along microtubule, and Obsolete ubiquitin-dependent ERAD pathway. Each is linked with UVRAG-DT in more than 17 cancer types. Because this analysis shows association rather than direction, both UVRAG-DT-to-partner and partner-to-UVRAG-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of centrosome duplication grouped by UVRAG-DT-low versus UVRAG-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UVRAG-DT→partner) and Y-score (partner→UVRAG-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of centrosome duplication →	+0.046	+0.181	<.001	<.001	3	18
STAD	Transport along microtubule →	+0.044	+0.176	<.001	<.001	3	18
STAD	Obsolete ubiquitin-dependent ERAD pathway →	+0.050	+0.175	<.001	<.001	3	18
STAD	Regulation of double-strand break repair →	+0.048	+0.199	<.001	<.001	3	17
STAD	Positive regulation of DNA metabolic process →	+0.052	+0.202	<.001	<.001	3	17
STAD	Regulation of DNA repair →	+0.053	+0.219	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,104 associations by consensus.

Negative regulation of centrosome duplication by UVRAG-DT expression — STAD

Explore this box plot interactively →