UVRAG-DT

Across TCGA pan-cancer cohorts, UVRAG-DT RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated UVRAG-DT data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher UVRAG-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UVRAG-DT expression acts as an unfavorable survival marker, although some lineages such as THCA and UVM show a favorable association.

ACC, THYM, and CHOL are the cancer types where UVRAG-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	II,III,IV	0.207	0.625	.006	36	view →
THYM	OS	Median	II,III,IV	0.698	1.000	.001	33	view →
CHOL	DFS	Quartile	II,III,IV	0.134	0.540	.002	26	view →
THCA	DFS	Tertile	All	0.890	0.733	.009	26	view →
KICH	OS	Tertile	II,III,IV	0.816	1.000	.008	22	view →
COAD	DFS	Quartile	II,III,IV	0.389	0.641	.004	18	view →
GBM	OS	Tertile	All	0.223	0.559	<.001	18	view →
UVM	OS	Tertile	All	0.866	0.482	.025	15	view →
KIRP	DFS	Tertile	All	0.421	0.752	.005	11	view →
DLBC	DFS	Median	IV	1.000	0.510	.030	8	view →
LAML	DFS	Tertile	All	0.466	0.642	.040	6	view →
ESCA	DFS	Median	All	0.452	0.602	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

UVRAG-DT–ACC (DFS)

Open the ACC breakdown →