Q-omics provides the consensus-scored UVRAG-DT profile across patient tissues and cancer cell-line models. UVRAG-DT expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, UVRAG-DT is differentially expressed in 12, with the highest sampling consensus in KICH. Additionally, UVRAG-DT RNA expression shows 12,589 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and KICH as cancer lineages where UVRAG-DT shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for UVRAG-DT — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes UVRAG-DT survival associations across molecular data types. UVRAG-DT RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible UVRAG-DT RNA expression–survival associations across cancer types. High UVRAG-DT expression shows unfavorable associations in ACC, THYM, CHOL, KICH and COAD, but favorable associations in THCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .006). Together, the overview and detailed table identify ACC as the clearest survival context for UVRAG-DT RNA expression.
This table summarizes UVRAG-DT tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for UVRAG-DT. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. UVRAG-DT shows lower tumor expression in KICH, THCA and BRCA and higher tumor expression in BLCA, STAD and COAD. The KICH box plot shows higher UVRAG-DT RNA expression in normal versus tumor tissue (log2 FC = −0.565, t-test p < 0.001).
This table shows molecular features associated with UVRAG-DT in patient tissues and cancer cell lines. In patient samples, UVRAG-DT shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
