USP9YP10

Across TCGA patient cohorts, USP9YP10 RNA expression is significantly associated with the mutation status of many other genes, with 2,050 significant associations in total. LGG shows the largest number of these associations.

The most reproducible USP9YP10-associated genes across cancer lineages are SIGLEC8, KDM6B, and SLC15A4. Each is linked with USP9YP10 in more than 2 cancer types. Because this analysis shows association rather than direction, both USP9YP10-to-partner and partner-to-USP9YP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC8 grouped by USP9YP10-low versus USP9YP10-high in LGG.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP9YP10→partner) and Y-score (partner→USP9YP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	SIGLEC8 →	+7.977	+0.049	.007	<.001	3	3
LGG	KDM6B →	+7.977	+0.049	.007	<.001	3	3
LGG	SLC15A4 →	+7.977	+0.049	.007	<.001	3	3
LGG	CDC42BPA →	+7.977	+0.049	.007	<.001	3	3
LGG	ROBO4 →	+7.977	+0.049	.007	<.001	3	3
LGG	VPS16 →	+7.977	+0.049	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,050 associations by consensus.

SIGLEC8 by USP9YP10 expression — LGG

Explore this box plot interactively →