USP9YP10

Across TCGA pan-cancer cohorts, USP9YP10 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated USP9YP10 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher USP9YP10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated USP9YP10 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

THCA, BLCA, and READ are the cancer types where USP9YP10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.125	0.927	<.001	102	view →
BLCA	OS	Tertile	All	0.133	0.720	.004	99	view →
READ	OS	Tertile	All	0.054	0.933	<.001	72	view →
LUSC	DFS	Tertile	All	0.159	0.661	.004	72	view →
HNSC	OS	Tertile	All	0.174	0.710	.012	45	view →
CESC	DFS	Tertile	II,III,IV	0.140	0.785	<.001	36	view →
PAAD	OS	Tertile	All	0.138	0.590	<.001	27	view →
COAD	DFS	Tertile	All	0.273	0.697	.003	18	view →
KIRC	DFS	Tertile	All	0.124	0.627	.003	18	view →
ESCA	DFS	Tertile	II,III,IV	0.675	0.449	.020	12	view →
GBM	OS	Tertile	All	0.086	0.415	.010	9	view →
STAD	DFS	Tertile	All	0.431	0.566	.030	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

USP9YP10–THCA (OS)

Open the THCA breakdown →