USP54

Across TCGA patient cohorts, USP54 protein abundance is significantly associated with the RNA expression of many other genes, with 6,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP54-associated genes across cancer lineages are RNU6-883P, RPS26P41, and SMAGP. Each is linked with USP54 in more than 6 cancer types. Because this analysis shows association rather than direction, both USP54-to-partner and partner-to-USP54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP54 versus RNU6-883P in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP54→partner) and Y-score (partner→USP54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-883P →	+1.448	+0.430	<.001	<.001	3	7
GBM	RPS26P41 →	+1.121	+0.522	<.001	<.001	3	7
LUAD	SMAGP →	+0.877	+0.280	<.001	.004	3	4
UCEC	SPINK13 →	+0.947	+0.247	<.001	.007	3	3
OV	DRP2 →	-0.502	-0.575	<.001	.001	3	3
OV	MAP4K1 →	-0.891	-0.692	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,040 associations by consensus.

USP54 vs RNU6-883P — UCEC

Explore this scatter interactively →