USB1

Across TCGA patient cohorts, USB1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,684 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible USB1-associated genes across cancer lineages are IL1A, LARP1B, and SPIN3. Each is linked with USB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both USB1-to-partner and partner-to-USB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USB1 versus IL1A in PDAC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USB1→partner) and Y-score (partner→USB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	IL1A →	+1.460	+0.802	<.001	<.001	3	3
HNSC	LARP1B →	-0.562	-0.341	<.001	<.001	3	3
HNSC	SPIN3 →	-0.538	-0.308	.001	.001	3	3
BRCA	SLC35E2A →	-0.610	-0.593	.006	.002	3	3
HNSC	LARGE-AS1 →	-0.766	-0.336	<.001	<.001	3	3
UCEC	PTPN23 →	-0.522	-0.492	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,684 associations by consensus.

USB1 vs IL1A — PDAC

Explore this scatter interactively →