UNC119B

Across TCGA patient cohorts, UNC119B mutation is significantly associated with the RNA expression of many other genes, with 871 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UNC119B-associated genes across cancer lineages are LINC01072, LINC02053, and HAO1. Each is linked with UNC119B in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC119B-to-partner and partner-to-UNC119B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by UNC119B-low versus UNC119B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC119B→partner) and Y-score (partner→UNC119B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01072 →	+0.192	+2.810	<.001	.002	3	2
SKCM	LINC02053 →	+0.030	+4.993	<.001	.002	3	2
SKCM	HAO1 →	+1.418	+3.746	<.001	.006	3	2
BRCA	MIR3118-3 →	+0.558	+8.471	<.001	.005	3	1
UCEC	PPIL2 →	+0.447	+3.595	.004	.001	3	1
UCEC	CRYBB2P1 →	+0.628	+3.606	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 871 associations by consensus.

LINC01072 by UNC119B expression — UCEC

Explore this box plot interactively →